When it comes to describing the smallest quantity of something, there are plenty of synonyms that can be used instead of the phrase "lowest amount". For instance, "minimum" is a great option to use in this context, as it suggests the smallest or least possible amount of something. Other synonyms include "smallest", "tiniest", "lowest level", "bottom", "least", "slightest", "minimal", and "scant". Depending on the context and tone of the sentence, each of these words can be used to describe a different degree of smallness, making them useful for anyone looking to add variation to their writing or speaking.