Replenish means to add or fill something up again. Some antonyms for replenish are empty, deplete, reduce, decrease, drain or take away. When you empty something, you are removing everything from it, leaving it with nothing inside. Deplete suggests the complete exhaustion of a resource, and it can be used to describe a wide range of resources, including finances, energy, or natural resources. Reduce means to make something smaller or less in quantity, while decrease is a synonym that specifies a quantity or number. To drain is to remove all the liquid or energy from something, whereas to take away means to remove something from a particular place or person.