There are several synonyms for the phrase "make a sucker out of," which means to deceive or cheat someone. One alternative is "take for a ride," which suggests that the person is being taken on a journey they did not expect. Another option is "hoodwink," which implies a deliberate attempt to fool someone. "Bamboozle" also works as a synonym, as it connotes being tricked or fooled. "Dupe" is another useful synonym, as it suggests being taken advantage of through naivety or trust. Ultimately, all of these phrases convey the same sense of betrayal and the need for caution when dealing with others.