Synonyms for Most anguished:

• adj.

  •grief-stricken (adjective)
  • heartbroken,
  • anguished,
  • hurting,
  • devastated,
  • melancholy,
  • overcome,
  • cheerless,
  • unhappy,
  • inconsolable,
  • dejected,
  • distressed,
  • troubled,
  • morose,
  • despairing,
  • heavyhearted,
  • depressed,
  • miserable,
  • down,
  • woebegone,
  • heartsick.
  •tragic (adjective)
  • dire,
  • unfortunate,
  • ill-fated,
  • cataclysmic,
  • fatal,
  • dreadful,
  • deadly,
  • calamitous,
  • painful,
  • adverse,
  • deathly,
  • ill-starred,
  • appalling,
  • heartbreaking,
  • ruinous,
  • hapless,
  • harrowing,
  • awful,
  • terrible,
  • destructive,
  • disastrous,
  • heart-rending,
  • deplorable,
  • fateful,
  • grim,
  • crushing,
  • shocking.
  •troubled (adjective)
  • displeased,
  • inconvenienced,
  • terrified,
  • disconcerted,
  • distraught,
  • plagued,
  • provoked,
  • chagrined,
  • Harrowed,
  • worried stiff,
  • overwrought,
  • miffed,
  • riled,
  • flustered,
  • discombobulated,
  • beset,
  • aggravated,
  • concerned,
  • pestered,
  • in a tizzy,
  • ruffled,
  • irritated,
  • frightened,
  • irked,
  • scared,
  • exacerbated,
  • put out,
  • harried,
  • mortified,
  • puzzled.
  •uncomfortable (adjective)
  • disturbed,
  • confused,
  • fatigued,
  • annoyed,
  • sore,
  • wracked,
  • weary,
  • galled,
  • aching,
  • discomposed,
  • smarting,
  • vexed,
  • exhausted,
  • discomfited,
  • disquieted,
  • ill at ease,
  • tired,
  • nervous,
  • awkward,
  • angry,
  • stiff,
  • chafed,
  • harsh,
  • embarrassed,
  • comfortless,
  • uneasy,
  • restless,
  • self-conscious,
  • worn.
  •uneasy (adjective)
  • insecure,
  • Wrung,
  • in turmoil,
  • alarmed,
  • worried,
  • harassed,
  • perplexed,
  • perturbed,
  • jittery,
  • suspicious,
  • upset,
  • restive,
  • unquiet,
  • irascible,
  • jumpy,
  • anxious,
  • unsettled,
  • apprehensive,
  • agitated,
  • palpitant,
  • shaken,
  • all nerves,
  • fidgety,
  • dismayed,
  • fretful,
  • bothered,
  • on edge,
  • impatient,
  • constrained,
  • shaky,
  • unstable,
  • tense,
  • peevish,
  • fearful,
  • edgy,
  • afraid,
  • on the qui vive,
  • irritable,
  • precarious.
  •woeful (adjective)
  • heartrending,
  • catastrophic,
  • piteous,
  • cruel,
  • poor,
  • disappointing,
  • feeble,
  • rotten,
  • bad,
  • plaintive,
  • inadequate,
  • disgraceful,
  • mean,
  • paltry,
  • lousy,
  • sorry.

Antonyms for Most anguished:

• adj.

  • miserable
    good, cheerful, rich, merry, generous, wealthy, elated, happy, joyful.
  • pained
    collected.
  • tragic
    healthful, trivial, wholesome, great, fortunate, hopeful, comforting, joyous, wonderful, blessed, pleasing, advantageous, lucky, successful, unimportant, pleasant, healthy, excellent, nice, delightful, life-giving, worthwhile, calming, encouraging, harmless.
  • troubled
    pleased, untroubled, sane, balanced, comforted, unconcerned.
  • uncomfortable
    content, comfortable, Energized, fresh, lively, painless, calm, activated, easy, refreshed.
  • uneasy
    firm, unafraid, unworried, courageous, cool, peaceful, easy-going, quiet, Indubious, bold, strong, at ease, sound, sure, undoubted, steady, laid-back, confident, stable, certain, settled, Unfearful, brave, composed, definite.
  • woeful
    satisfactory, glad.