Granuloma venereum is a rare sexually transmitted disease caused by the bacterium Chlamydia trachomatis. It is characterized by the formation of ulcers or nodules in the genital area that can lead to scarring, chronic inflammation, and sexual dysfunction. Synonyms for granuloma venereum include lymphogranuloma venereum (LGV), tropical bubo, lymphopathia venereum, Durand-Nicolas-Favre disease, and nichols-serovar. LGV is the most widely recognized synonym and is commonly used to refer to the disease in most medical literature. However, it is essential to know all the synonyms to ensure prompt diagnosis, treatment, and prevention of the disease.