Synonyms for Once and again:

• adj.

  •double (adjective)
  • twice.

• a. & adv.

  •once in awhile (adjective, adverb)
  • most infrequently,
  • once awhile,
  • most occasionally.
  •Other relevant words: (adjective, adverb)
  • once in a while.

• adv

  •for the most part (adverb)
  • usually.
  •now and then (adverb)
  • not often,
  • once in a blue moon,
  • once in blue moon,
  • once or twice,
  • now and again,
  • once again,
  • now then,
  • every so often.
  •Other relevant words: (adverb)
  • on the whole,
  • by and large,
  • in the main,
  • routinely,
  • as is usual,
  • more often than not,
  • typically,
  • per usual,
  • as usual,
  • as is the custom,
  • every now and then,
  • once in awhile,
  • most often,
  • as a rule.

• adv.

  •every now and then (adverb)
  • ever so often.
  •from time to time (adverb)
  • from time time.
  •once in awhile (adverb)
  • more sometimes,
  • most periodically,
  • more periodically,
  • most sometimes,
  • more infrequently,
  • more sporadically,
  • most sporadically,
  • most irregularly,
  • more irregularly,
  • more occasionally.
  •Other relevant words: (adverb)
  • habitually,
  • ordinarily,
  • mainly.
  •routinely (adverb)
  • often,
  • naturally.
  •usually (adverb)
  • generally,
  • mostly,
  • regularly,
  • frequently,
  • consistently,
  • customarily,
  • normally,
  • commonly.

• Other synonyms:

  •Other relevant words (noun):
  • betimes,
  • every once in a while,
  • occasionally,
  • at intervals,
  • on occasion,
  • once more,
  • over again,
  • at various times,
  • now and then,
  • again,
  • Semioccasionally,
  • on divers occasions,
  • from time to time,
  • betweentimes,
  • another time,
  • at times.

Antonyms for Once and again:

• adv.

  • usually
    seldom, sometimes, unusually, rarely, infrequently, never, uncommonly, exceptionally.