Synonyms for By and large:

• adj.

  •en masse (adjective)
  • as a whole.

• adv

  •as a whole (adverb)
  • altogether.
  •for the most part (adverb)
  • usually.

• adv.

  •all (adverb)
  • mostly.
  •altogether (adverb)
  • en masse,
  • on the whole,
  • all in all,
  • for the most part,
  • all things considered.
  •generally (adverb)
  • commonly,
  • largely,
  • customarily,
  • principally,
  • primarily,
  • roughly,
  • habitually,
  • approximately,
  • normally,
  • chiefly.
  •largely (adverb)
  • mainly.

• Other synonyms:

  •Other relevant words:
  • effectually,
  • nearly,
  • broadly speaking,
  • essentially,
  • generally speaking,
  • to all intents and purposes,
  • virtually,
  • in particular,
  • pre-eminently,
  • substantially,
  • especially,
  • most of all,
  • Prevailingly,
  • in general,
  • above all,
  • on balance,
  • in the long run,
  • part,
  • whole,
  • almost entirely,
  • in all respects.

Antonyms for By and large:

• adj.

  • en masse
    one at a time, singly.

• adv.

  • altogether
    incompletely, partly.
  • generally
    rarely, sometimes, particularly, specifically, unusually, seldom, exactly.
  • usually
    never, uncommonly, exceptionally, infrequently.
  • Other antonyms:
    completely, absolutely, hardly, minimally, scarcely, barely, fully, categorically, just, unqualifiedly, perfectly, marginally, wholly, totally, entirely, thoroughly.