Assist is often associated with the act of helping, supporting or aiding someone in their endeavors. However, it can have antonyms that convey opposite meanings. The antonym for assist varies depending on the context. When used in terms of impeding or blocking something, the opposite of assist is hinder. When used in contrast with directing or leading, the opposite of assist would be to deter or impede progress. In situations where assistance is not required, neglect or hinderance can be the opposite of assist. These antonyms paint a different picture of the word assist and highlight its contrasting meaning.